"Next Level Growth" Extended GH / IGF

The Extended GH / IGF kit builds on the classic GHRH-plus-ghrelin secretagogue pairing by swapping in the DAC-modified form of CJC-1295 for longer receptor engagement, then adds IGF-1 LR3 to represent the downstream signaling step that growth hormone release ultimately triggers. This kit is built around three points along the same signaling cascade rather than three unrelated peptides.

CJC-1295 with DAC and Ipamorelin drive growth hormone release upstream, the same two-receptor logic used in the standard GH Secretagogue kit, while IGF-1 LR3 represents what happens downstream once growth hormone reaches the liver and stimulates IGF-1 production. Including all three lets researchers study the release side and the downstream signaling side in the same protocol.

What's Included in This Kit

• Vial 1, CJC-1295 w/ DAC (5mg): extended-duration GHRH receptor activation via its albumin-binding structure.
• Vial 2, Ipamorelin (5mg): ghrelin/GH secretagogue receptor activation with a narrow off-target profile.
• Vial 3, IGF-1 LR3 (1mg): IGF-1 receptor signaling and cellular proliferation, downstream of growth hormone release.

CJC-1295 with DAC: Extended Receptor Engagement

CJC-1295 with DAC is a GHRH analog modified with Drug Affinity Complex, a structural addition that binds serum albumin and extends how long the peptide stays active compared to CJC-1295 without DAC. That extended engagement window is the specific reason it is used here rather than the unmodified version used in the standard GH Secretagogue kit.

IGF-1 LR3: The Downstream Signaling Piece

IGF-1 LR3 is a long-acting analog of insulin-like growth factor 1, engineered with reduced binding to IGF-binding proteins so more of it remains bioavailable in research models. It is studied for IGF-1 receptor signaling and cellular proliferation, the downstream research area that GHRH/ghrelin-driven GH release is ultimately connected to. Researchers who want to examine the full arc from receptor activation to cellular signaling, rather than just the release event itself, are the intended audience for this kit.

Duration of Action as a Research Variable

One of the more practical reasons researchers choose the DAC-modified CJC-1295 over the standard version is the duration-of-action question itself. Native GHRH and unmodified CJC-1295 are cleared relatively quickly, which is useful for studying discrete, well-defined pulses, but less useful for research designs that need a sustained elevation in GHRH receptor activity over a longer observation window. The DAC modification's albumin-binding property is specifically what extends that window, making this kit the more appropriate choice for protocols where duration, not just pulse amplitude, is the variable under study.

Related Research Bundles

For the standard, non-DAC version of this pairing without the IGF-1 addition, see GH Secretagogue. For the earlier-generation secretagogue pairing, see Classic Secretagogue. Browse the full Peptide Bundles collection for the complete lineup.

All three vials ship individually labeled with compound name, strength, and batch lot number and are not co-formulated. Each is independently HPLC-verified for identity and purity before batch release.

This product is intended strictly for laboratory research use only. It is not approved for human consumption, therapeutic application, or diagnostic purposes.